April 24, 2024

Scientists Find Japanese Sensitivity May Extend Lifespan and Reduce Stress

Research shows that natto, a fermented Japanese soybean dish, may extend lifespan and improve stress resistance due to its Bacillus subtilis var. natto bacteria content. The study suggests potential benefits to human health and longevity if these effects are transferrable.

Consuming natto may help relieve stress.

As the saying goes, health is wealth and now new research suggests that the key to a healthier, less stressful society may be easily accessible and affordable food items.

A great example of such a food is the Japanese dish called natto. This food item is produced from soybeans that have been tenderized by boiling or steaming and then fermented with a designated bacterium Bacillus subtilis was. natto. This bacterium can be found in various environments such as soil, plants, animals, and even the human digestive system. Most of the natto consumed in Japan is made from Miyagino strain.

A research group led by Professor Eriko Kage-Nakadai at the Graduate School of Human Life and Ecology, Osaka City University, examined the effects of Bacillus subtilis was. natto consumption over the lifetime of the host using it Caenorhabditis elegans worms.

Japanese natto

Bacillus subtilis was. natto (Miyagino pressure) extends the life of the Caenorhabditis elegans through biological pathways related to innate immunity and longevity, and partially improves stress tolerance. Credit: Osaka City University

The researchers found that Caenorhabditis elegans nourished Bacillus subtilis was. natto had a significantly longer life span than those fed the normal diet, and further demonstrated that the p38 MAPK pathway and insulinA /IGF-1-like signaling pathway, known to be involved in innate immunity and lifespan, was associated with lifespan-enhancing effects Bacillus subtilis was. natto. They also examined stress tolerance, which has been shown to correlate with longevity, and found that resistance to UV light and oxidative stress is improved.

Professor Nakadai concluded, “For the first time, we have been able to demonstrate that the life-extending effects of Caenorhabditis elegans by ingesting the Bacillus subtilis was. natto. We hope that future experiments on mammals and epidemiological studies will help to achieve a healthy and longer-lived society if we can apply this research to humans.”

Reference: “Influence Bacillus subtilis was. natto on lifespan and stress resistance of Caenorhabditis elegans” by Nao Teramoto, Kanae Sato, Takayuki Wada, Yoshikazu Nishikawa and Eriko Kage-Nakadai, 20 Apr 2023, Journal of Applied Microbiology..
DOI: 10.1093/jambi/lxad082

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